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What is a microfluidic device?

Microfluidics is the engineering or use of devices that apply fluid flow to channels smaller than 1 millimetre in at least one dimension. Microfluidic devices can reduce reagent consumption, allow well controlled mixing and particle manipulation, integrate and automate multiple assays (known as lab-on-a-chip), and facilitate imaging and tracking.

What are open microfluidic devices?

Open microfluidic devices are also easy and inexpensive to fabricate by milling, thermoforming, and hot embossing. In addition, open microfluidics eliminates the need to glue or bond a cover for devices, which could be detrimental to capillary flows.

What is droplet-based microfluidics?

Droplet-based microfluidics is a subcategory of microfluidics in contrast with continuous microfluidics; droplet-based microfluidics manipulates discrete volumes of fluids in immiscible phases with low Reynolds number and laminar flow regimes. Interest in droplet-based microfluidics systems has been growing substantially in past decades.

What is microfluidic cell culture?

For example, eukaryotic cells have linear dimensions between 10 and 100 μm which falls within the range of microfluidic dimensions. A key component of microfluidic cell culture is being able to mimic the cell microenvironment which includes soluble factors that regulate cell structure, function, behavior, and growth.

What is active microfluidics?

Active microfluidics refers to the defined manipulation of the working fluid by active (micro) components such as micropumps or microvalves. Micropumps supply fluids in a continuous manner or are used for dosing. Microvalves determine the flow direction or the mode of movement of pumped liquids.

What are paper-based microfluidic devices?

Paper-based microfluidic devices are often referred to as microfluidic paper-based analytical devices (μPADs) and can detect such things as nitrate, preservatives, or antibiotics in meat by a colorimetric reaction that can be detected with a smartphone.

Energie oogsten

Energie oogsten is het proces waarbij energie wordt onttrokken uit de directe omgeving en vervolgens wordt opgeslagen voor gebruik in kleinschalige draadloze systemen. Voorbeelden van dergelijke bronnen zijn stralingsenergie, thermische energie, mechanische energie, magnetische energie en biochemische energie opgeslagen energie is gering, maar voldoende om …

Microfluïdische druksensor Markt 2031: rapport over omvang

"Gedetailleerde studie van de Microfluïdische druksensor-markt (2024-2031) Nieuwe analyse van Microfluïdische druksensor Marktoverzicht, uitgavenanalyse, import, segmentatie, belangrijkste spelers en kansenanalyse 2024-2031. Het onderzoek omvat ook een diepgaande concurrentieanalyse van de belangrij

Microfluidics

Microfluidics articles from across Nature Portfolio. Atom; RSS Feed; Definition. Microfluidics is the engineering or use of devices that apply fluid flow to channels smaller than …

Recent advances in droplet microfluidics for microbiology

The above features collectively make droplet microfluidics a robust and valuable platform for microbiology studies. Combining with advanced sequencing technologies [18] or dynamic fluorescence imaging [19], droplet microfluidics helps bring microbiologists closer to the ultimate goal of microbial ecology: observing and understanding who does what, when, where …

Mikrofluidik und On-Chip Devices

Patrick Witzel. Mikrofluidik und Simulation. Fraunhofer-Projektzentrum für Stammzellprozesstechnik Neunerplatz 2 97082 Würzburg. Telefon +49 931 30-85183

Mikrofluidik und Einzelzelltechnologien

Wir bieten anwendungsnahe und kundenspezifische Entwicklungen von Verfahren und Prototypen für die Prozessierung und Handhabung von anspruchsvollen biologischen Proben an. Ein Schwerpunkt ist die Manipulation …

Mikrofluidik

Lasertechnik trägt in unterschiedlichen Märkten zur Lösung anspruchsvoller Aufgabenstellungen bei. Ob als Werkzeug in der Automobilfertigung, als Messmittel im Umweltbereich, als Diagnose- oder Therapieinstrument in der …

Recent Advances in Microfluidic Technology for Bioanalysis and ...

Microfluidic technology has multiple benefits for bioanalytical procedures. Obviously, the miniaturized devices facilitate processing and analyzing of small sample volumes, in the range of μL to pL.

Computational Microfluidics for Geosciences

1 Earth Sciences Institute of Orléans, University of Orléans-CNRS-BRGM, Orléans, France; 2 Institute of GeoEnergy Engineering, Heriot-Watt University, Edinburgh, United Kingdom; Computational microfluidics for geosciences is the …

Detection techniques | Microfluidics | Sirris

In dit artikel van onze serie over microfluïdische lab-on-chips bespreken we enkele basisprincipes voor het detecteren of kwantificeren van de hoeveelheid biochemisch analyt in een testmonster. De detectieprincipes bestaan uit één of meer van de volgende elementen: de bioreceptor die heel specifiek aan het analyt kan binden,

Applications of microfluidics in biosensing | Discover ...

Microfluidic devices have become a vastly popular technology, particularly because of the advantages they offer over their traditional counterparts. They have such a wide range of uses and can make complex tasks quite efficient. One area of research or work that has benefited greatly from the use of microfluidics is biosensing, where microfluidic chips are integrated into …

Mikrofluidik

microfluïdische systemen voor celculturen een noodzaak geworden. Ze bieden een gecontroleerde omgeving waarin met meer precisie en een verminderd verbruik van reagentia …

Microfluidic devices voor medische toepassingen

In de jaren ''90 ontwikkelden onderzoekers de eerste microfluide systemen gebaseerd op microchips uit de elektronica voor toepassing in biologisch, chemisch en biomedisch onderzoek. Het eenvoudigste huidige …

Introduction: Microfluidics | Chemical Reviews

Microfluidics refers to a set of tools for manipulating fluids and materials at the scale typically of a few to hundreds of microns. The ideas and strategies for experimental measurements have continually expanded over the …

Towards Small Scale: Overview and Applications of ...

Thanks to recent and continuing technological innovations, modern microfluidic systems are increasingly offering researchers working across all fields of biotechnology exciting new possibilities (especially with respect to facilitating high throughput analysis, portability, and parallelization). The advantages offered by microfluidic devices—namely, the substantially …

Mikrofluidisches Microarray für die Einzelzellanalyse

In this paper we present the development of a microfluidic microarray for trapping and analysis of single cells. The system consists of a PDMS/glass chip with a microfluidic channel network and hydrodynamic traps. …

Microfluidics: Innovations in Materials and Their Fabrication and ...

Polymethyl methacrylate (PMMA) is widely used in research laboratories because it is optically transparent and can be manipulated with fabrication methods such as hot embossing, laser ablation, or precision milling.

The present and future role of microfluidics in biomedical research

Recent progress in the various lab-on-a-chip microtechnologies is reviewed and the clinical and research areas in which they have made the greatest impact are discussed. Microfluidics exploits the ...

Microfluïdica en procesminiaturisatie voor toepassingen in de ...

Microfluïdische technologie is toepasbaar in uiteenlopende sectoren zoals chemie, farmaceutica, voeding, biowetenschappen en medische diagnostiek. Tijdens dit seminarie demonstreert Sirris de technieken die in België beschikbaar zijn om een volledig aangepast apparaat te ontwikkelen, specifiek voor uw toepassing en klaar voor massaproductie. ...

Microfluidic cell culture

OverviewFabricationAdvantagesCulture platformsApplications of cells in microfluidic systemsMulti-culture in microfluidicsControlling cell microenvironmentSee also

Microfluidic cell culture integrates knowledge from biology, biochemistry, engineering, and physics to develop devices and techniques for culturing, maintaining, analyzing, and experimenting with cells at the microscale. It merges microfluidics, a set of technologies used for the manipulation of small fluid volumes (μL, nL, pL) within artificially fabricated microsystems, and cell culture, which involves the maintenance and growth of cells in a controlled laboratory environment. Microfluidic…

The origins and the future of microfluidics

What is microfluidics? It is the science and technology of systems that process or manipulate small (10–9 to 10–18 litres) amounts of fluids, using channels with dimensions of tens to hundreds of micrometres.

Mikrofluidik – Übersicht | Malvern Panalytical

Durch die Kombination der patentierten Gitter-gekoppelten Interferometrie (GCI)-Technologie mit verstopfungsfreier Mikrofluidik setzt das Creoptix WAVEsystem neue Maßstäbe für die Bindungskinetikanalyse. Unser innovativer Ansatz bietet eine überlegene Signal- und Zeitauflösung im Vergleich zu anderen Formen der markerfreien Erkennung und liefert Ihnen …

MICROPLAITE project

Dit unieke microfluïdische platform zal de micro-omgeving van natuurlijke weefsels nabootsen, waardoor er minder proefdieren nodig zijn voor in vivo-tests. Ontdek hoe dit project, dat experts uit Frankrijk, Wallonië en Vlaanderen samenbrengt, de ontwikkeling van medische hulpmiddelen kan transformeren met snellere, nauwkeurigere en ethisch verantwoorde oplossingen.

Kennispark Twente op de schop: ''Gloednieuw pand voor …

''Gloednieuw pand voor productie microfluidische chips'' Elke dag werken kennisinstellingen en bedrijven op Kennispark Twente aan de nieuwste innovaties die van groot belang zijn voor de dag van morgen.

Mikrofluidisches Microarray für die Einzelzellanalyse | e+i ...

In this paper we present the development of a microfluidic microarray for trapping and analysis of single cells. The system consists of a PDMS/glass chip with a microfluidic channel network and hydrodynamic traps. The microfluidic chip was fabricated with MEMS technology and thereafter characterized by experimental flow visualization using fluorescent …

Microfluidics: A general overview of microfluidics

Microfluidics is both the science which studies the behaviour of fluids through micro-channels, and the technology of manufacturing microminiaturized devices containing chambers and tunnels through which fluids flow or are confined. Microfluidics deal with very small volumes of fluids, down to femtoliters (fL) which is a quadrillionth of a liter. Fluids behave very differently on the ...

Kennispark Twente op de schop. ''Gloednieuw pand voor …

Fabriek voor microfluïdische chips. Dat Micronit fors gaat uitbreiden op Kennispark, het bedrijf produceert en ontwikkelt lab on a chip producten (Bio chips) en micro-elektromechanische systemen (MEMS) waarmee lichaamseigen vloeistoffen op zeer kleine schaal geanalyseerd en bewerkt kunnen worden. Ook in de coronacrisis bewees het haar ...

A complete microfluidics overview: Explore Cutting-Edge

Microfluidics for Miniaturized Laboratories. A key concept related to microfluidics is the ability to integrate operations that would typically require a whole laboratory into a simple micro-sized system.Currently, a traditional scale-up is substituted in microfluidic systems by multiplexing, drawing on the compact size of the device to dramatically shorten the time from formulation to …

Microfluidic chips: recent advances, critical strategies in design ...

A Diagrammatic representation of the microfluidic chip; B type of microfluidic chips and C application of microfluidic chips. Types of microfluidic chips based on device configuration. There are different types of microfluidic chips are designed, namely droplet microfluidic chip (Mashaghi et al. 2016; Seemann et al. 2011), organ-on-chip (OOC) (Wu et al. 2020), microfluidic hydrogel …